COOP notes #8
Today we'll do Chapters 22 & 5

GRAPHICAL ANALYSIS

Graphical analysis is based on the Maddox components/classifications where Maddox describes four stimuli to accommodation and convergence (tonic innervation, proximal cue [spatial cue] and disparity [retinal cue] and cross-links [AC/A and CA/C]).
Clinical case analysis is based on the assumption that there is a linear summation of these components: When we converge and accommodate, we're summing those 4 components of accommodation and convergence linearly. 60 years ago, Dr. Morgan and his colleagues took the Maddox concept and put it in a graphical format so clinically you can write your data in a form that would show how accommodative vergence, fusional vergence, and tonic vergence would add up together. This graphical analysis technique allows you to predict what real world stimuli your patient can respond to with comfort and helps you to prescribe lenses and prisms.

Today we'll show how Maddox components are represented in this graphical representation.



The horizontal axis is convergence & divergence. The zero is when eyes are parallel looking at infinity. Convergence responses to BO prism are to the right of zero and divergence responses to BI prism are to the left of zero.

Test at 2 distances: At 6 m (or infinity) you have zero stimulus to convergence & accommodation (appropriate horizontal scale is at bottom of graph). Then test at 40 cm (appropriate horizontal scale is at top of graph). Therefore, you'll have 2.5D stimulus to accommodation. Level of convergence at 40 cm is 2.5 meter angles. Convert that to prism diopters by multiplying it by PD.
e.g. if PD = 6 cm, then (6cm)(2.5D) = 15 prism diopters.

On the graph, go to 15 prism diopter stimulus of of convergence and 2.5 D stimulus to accommodation at 40 cm . Vertical and horizontal lined drawn through these two intersect (2.5D of accommodation & 15 prism diopter of convergence), at a point represents the near stimulus at 40 cm.

You can also plot a point for 20 cm of viewing distance: Therefore it would be 5D of stimulus to accommodation & (5)(6) = 30 prism diopters of convergence. If you connect all these real world stimuli points, it forms a line called the "Demand Line" or "Donder's Line" or the "One to One Line." Mostly it's called the Demand Line because it represents the stimulus to accommodation and convergence. That single line represents all physical stimuli in real space at a viewing distance.
The demand line varies for different PD distances. For a 7cm PD, there are more prism diopters of convergence for every diopter of accommodation. If your eyes are really far apart you have to converge a lot more to see the same point than if your eyes are closer together. Therefore, the demand line depends on the PD distance.


3 Components of Maddox Classification are represented by the graph.

1. Tonic vergence
2. Fusional vergence
3. Accommodative vergence

How do we represent tonic vergence? Remember tonic vergence brings us from anatomical position of rest to physiological position of rest. When we measure our phorias, we're measuring the physiological position of rest which is basically,

Physiological position of rest = Demand + Phoria (vergence error)

e.g. If you're 3 exo at near & 1 exo at far & the near demand is 15 prism diopters, then you diverge by 3 prism diopters from 15 prism diopters to plot the position of rest at near (sum of physiological position of rest and any accommodative vergence). As a result, you are only converging 12 prism diopters when one eye is occluded.

To plot the phoria on the graph, draw an X to the left (if exo) or to the right (if eso) of the demand line at the corresponding test distance. Phoria is the distance between the demand line to that data point (3 prism diopters). The phoria is an error of vergence, so under monocular viewing conditions, you converged 12 prism diopters when ideally you were supposed to converge 15 prism diopters. Next connect the near and far phorias points with a single line. That line is called the "Phoria Line."

What is interesting about the phoria line is that you can measure phoria at 40 cm (near) and at 6 m (far). Now when we connect the 2 points (which gives us the phoria line) we can predict the phoria at any other viewing distance. Phoria is the separation between the phoria line and the demand line at a specific viewing distance. Therefore, according to the graph at 20 cm viewing distance, phoria is ~7 prism diopters. Phoria is the amount of error by which patients miss the mark.

Phoria at near = Phoria at far + Accommodative vergence.

If accommodative vergence is constant,
then Calculated AC/A ratio = reciprocal of the slope of phoria line

Lower AC/A ratio -- steeper phoria line. So when this line is vertical, then AC/A = 0. When AC/A = PD(in cm), then slope of phoria line equals slope of demand line. e.g. If AC/A ratio is 6/1 & PD=6cm, then the phoria line would be parallel to the demand line. But usually AC/A is less than the demand line (that is, more vertical).
Next step is to measure the convergence & divergence limits. To do this you need a Risley prism. The Risley prism is made of 2 large prisms. They spin so that sometimes their bases are on opposite sides and this gives zero power. Other times their bases are on the same side and in this case the total power is the sum of the two.

[Picture]







You can set up this prism to stimulate convergence of the eye until the patient sees double (cannot fuse) and also stimulate divergence of the eye until the patient sees double.
We can plot how much we can converge & diverge from that phoria line. That range ends up being a constant distance from the phoria line. If you consider the phoria line as the fusion free position of rest which is the sum of tonic and accommodative vergence, what that means is that you have a constant amount of fusional convergence or divergence you can add at any viewing distance.You'll find that convergence range with prism is nearly constant for all viewing distances for that phoria line (it increases slightly with proximity due to proximal vergence). This means that we are adding a constant amount of (+) positive fusional convergence to a constant amount of accommodative vergence to a constant amount of tonic vergence. The graph represents this linear summation.

What you end up with is a parallelogram which represents a combination of all prism and lens stimuli which your binocular system can respond to with clear, single binocular vision. So you can converge or diverge to see singly & adjust your focus to see clearly. Therefore you can converge & accommodate accurately but only to stimuli that lie inside the parallelogram.

This parallelogram is called the "Zone of Clear, Single Binocular Vision". This parallelogram gives you a lot of predictive power. The top of the zone is limited by the amplitude of accommodation.



The range of disparity vergence is called fusional (positive and negative fusional convergence PFC & NFC) when measured with respect to the phoria line and relative (positive and negative relative convergence PRC & NRC)when measured with respect to the demand line.

Relative Convergence measurement procedure:
Assume PD = 6 cm. Start with zero prism. Stimulus is simply 40 cm. Therefore convergence stimulus = 15 prism diopters (= 2.5D x 6 cm) and accommodation stimulus = 2.5D. Then start adding prism until you see double. We call that relative convergence because it is relative to the demand line. Sometimes a patient extends the range of singleness by purposely increasing or decreasing accommodation to add or subtract a little accommodative vergence. This will result in a visible blur of the target. When this occurs, the amount of prism is called the blur point. We plot the blur point on the graph to represent the limits of fusional vergence that is unaided by accommodative vergence.

The width of the zone from the phoria line is nearly constant and is called "fusional convergence range". The zone tends to be parallel to the phoria line. If slope of phoria line is different from the slope of the demand line then the distance from the fusion limit from demand line (relative vergence) will change with viewing distance.

Clinically we measure relative fusional convergence but we really want to know the absolute fusional convergence from the phoria line. To get that, subtract phoria from (+) relative convergence.

e.g. if you can converge 20 prism diopters from the demand line, and your phoria is 5 eso, then your actual fusional convergence is 15. Fusional convergence is relatively constant at all viewing distances. Fusional vergence is the actual physiological property of the Maddox hierarchy but we measure relative fusional convergence which is the combination of fusional and phoria.

How do we use all this information?
e.g. person with PD = 6.4 cm
They're exophoric & get more exophoric as they come to nearer viewing distances. So slope of phoria line is steeper than demand line.
(+) relative convergence is getting smaller with nearer viewing distance.
(+) fusional convergence is staying relatively constant.
(-) relative convergence is getting bigger with nearer viewing distance (because we're getting more exospheric)
(-) fusional convergence is staying relatively constant (the distance
from phoria line).

2 Criteria to evaluate patient comfort clinically

1. Percival's Criteria: (see figure above)
a) The middle 1/3 of the zone of clear single binocular vision (shaded region) is the range where we could respond comfortably. Percival said the demand line should lie within that range. If you're very exo the demand line would be on the right half of the zone; therefore we would prescribe enough BI prism or (-) Lens to slide demand line leftward to within the middle third of the zone.
b) If patient doesn't have symptoms of binocular stress, dont prescribe anything even if you find an unusual data point. However be sure lack of symptoms is not caused by avoiding reading.
c) Always correct vertical phoria before horizontal phoria. Vertical phoria will disrupt binocular vision & decrease range of horizontal convergence.

2. Sheard's criteria:
So how do we correct exophorias? When we converge the eyes to overcome the exo, we dont want to use more than half of our relative vergence range (the reserve) or 2/3 of our fusional convergence range. You always want the amount of convergence beyond the demand point (relative vergence or the reserve) to be 2 times the amount of phoria (the demand), which means you're only going to be using 1/3 of the total positive fusional vergence range to overcome this phoria.

Reserve fusional vergence (which is = positive relative convergence for exo) or (= excessive fusional vergence) should be at least 2 times the amount of phoria.

Positive relative convergence should be at least twice as great as the phoria. This is a more exact criteria than Percival's.

Eg. In clinic, if patient is 5 exo & positive relative convergence = 10 BO, the patient just meets Sheard's criteria. But if the patient was 5 exo & positive relative convergence = 5, this would mean they had to use up 1/2 of the total range of fusional convergence to see singly (demand equaled the reserve) and they're going to get headaches. So prescribe BI prism which slides the demand line to the left to decrease the phoria & increase the range of relative convergence. The minimum correction in this example would be to reduce the phoria to 3.33 exo or 1/3 the fusional vergence range (10 BO).

Correction scheme is always the same: Prescribe prism &/or lenses that move real world (demand line) so it falls somewhere within the center of zone of clear, single BV and also so that the demands on fusion don't exeed 1/3 of the potential range of fusion.

All this analysis is based on the Maddox concept that you linearly sum fusional vergence with accommodative vergence with tonic vergence.

Homework assignment

Plot out the person's zone of clear, single BV. On the graph, look at the slope of the phoria line and how it differs from the demand line. Look at the slope of BO & BI limits as relative to phoria & demand lines & how they're parallel to one another. They fan out symmetrically about one of those 2 lines & that fanning out has to do with proximal convergence. The range that we converge/diverge our eyes increases a little more with near viewing distance because of proximity.

Chapter 5

3 sources of oculomotor problems:
1. Congenital
2. Developmental
3. Aquired. (Recent onset & usually more serious problems can be due to trauma)

3 Kinds of eye movement problems:
1. Strabismus (phoria): deviation of one eye. Eye alignment problem.
2. Nystagmus: unsteadiness of eye. Stabilization & vestibular problem.
3. Saccadic disorder: some quick movements are abnormal

Strabismus

1. Comitant: deviation of eye stays constant at different direction of gaze. It can change with viewing distance. It can be congenital &/or developmental. You can use Sheard or Percival criteria to correct if the strabismus is not too large.
2. Noncomitant: angle between eyes varies with different directions of gaze. It is usually acquired. Use surgery &/or eye exercises for treatment. We can use other muscles in the eye to compensate for vertical movements because have 2 sets of muscles in the vertical direction (recti & obliques) but horizontal movements cannot be compensated by other muscles.

Causes of noncomitant can be muscle damage like Myasthinia gravis or trauma. Usually cranial nerves (especially III & VI) are affected because they are long and more tortuous pathways. Try to localize the site of the problem: muscle or nerve or somewhere more central.

Orbital mechanics

In order to predict the action of any muscle, we need to know the orientations of eye muscles inside the orbit & around the globe & also where the muscles are with respect to the head & visual axis.

There are three sets of canals that code motion of our head in 3D space:
1. Anterior canal
2. Posterior canal
3. Horizontal canal (lies in horizontal plane)

These canals lie in 3 planes. The posterior canal on the right side lies in a common plane as the anterior canal on the left side. The posterior canal on the left side lies in a common plane as the anterior canal in the right side.

There are also planes that the eye muscles lie in.



Vertical recti lie in a common plane. Obliques lie in another plane that nearly runs perpendicular to the vertical recti plane.

Muscle planes of vertical recti & obliques run aproximately parallel to the canal planes. That means muscles are there to respond to the canals. If we rotate our head in a meridian, we stimulate some combination of these canals & these canals go to the muscles that run parallel to them. Our muscle would counter-roll & keep our eyes stationary. Our eyes are like ocular gyroscopes to keep our eyes steady in space while our head rotates. This is not unique to primates.

Vertical recti forms an angle of 23 degrees with respect to the medial wall. Obliques form an angle at 51 degrees.
Rabbit eyes point off to the side
Cat eyes point forward.

The muscle planes for recti & obliques are parallel to the canal planes for both rabbits & cats. The only difference in the 2 animals is that during evolution, the visual axis is moved forward but the eye muscles didn't move to allow for stereo vision.

The goal of orientation of eye muscles is to remain parallel to the vestibular canals.

When obliques contract, it is causing the same motion of the globe in cats& rabbits but the effect on the motion of the visual axis is different. The difference is where the visual axis is pointing relative to the muscle plane. In rabbits, the visual axis is pointing temporal from the muscle plane of the recti. In cats, it is pointing directly along the axis of the vertical recti. In humans, the visual axis is nasal ward from the vertical recti.

Therefore in cats, vertical recti acts as pure elevators because the visual axis is already pointing along the axis of that muscle.

In rabbits, the superior rectus (SR) contracts to elevate the eye. The superior oblique (SO) contracts to elevate the eye. In cats, Obliques act as pure torters. In humans, SO depresses the visual axis but in the rabbit, SO elevates the visual axis. The difference is due to where visual axis is pointing. But the globe is making identical rotations as in cats, rabbits & humans. So it is important to know where the muscle planes & visual axes are and how the visual axis moves as we contract the muscle in a plane.
The actions of the individual extraocular muscles starting with the eye in primary position of gaze are indicated in the figures below.